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2018年發表的論文   spacer
  1. Alifu N, Zebibula A, Qi J, Zhang H, Sun C, Yu X, Xue D, Lam JWY, Li G, Qian J and Tang BZ (2018). Single-Molecular Near-Infrared-II Theranostic Systems: Ultrastable Aggregation-Induced Emission Nanoparticles for Long-Term Tracing and Efficient Photothermal Therapy. ACS Nano. 12(11):11282-11293.

  2. Cao W, Lin S, Xia QQ, Du YL, Yang Q, Zhang MY, Lu YQ, Xu J, Duan SM, Xia J, Feng G, Xu J and Luo JH (2018). Gamma Oscillation Dysfunction in mPFC Leads to Social Deficits in Neuroligin 3 R451C Knockin Mice. Neuron. 97(6):1253-1260.e7.

  3. Chen C, Liang Z, Zhou B, Li X, Lui C, Ip NY and Qu JY (2018). In Vivo Near-Infrared Two-Photon Imaging of Amyloid Plaques in Deep Brain of Alzheimer's Disease Mouse Model. ACS Chem. Neurosci. 9(12):3128-3136.

  4. Chen M, Xie W, Li D, Zebibula A, Wang Y, Qian J, Qin A and Tang BZ (2018). Utilizing a Pyrazine-Containing Aggregation-Induced Emission Luminogen as an Efficient Photosensitizer for Imaging-Guided Two-Photon Photodynamic Therapy. Chem. Eur. J. 24(62):16603-16608.

  5. Chen S, Liu J, Zhang S, Zhao E, Yu CYY, Hushiarian R, Hong Y and Tang BZ (2018). Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/dead cells. Mater. Horizons. 5:969-978.

  6. Chen S, Yu C, Rong L, Li CH, Qin X, Ryu H and Park H (2018). Altered Synaptic Vesicle Release and Ca2+ Influx at Single Presynaptic Terminals of Cortical Neurons in a Knock-in Mouse Model of Huntington's Disease. Front. Mol. Neurosci. 11:478 (1-17).

  7. Chen Y, Fu AKY and Ip NY (2018). Synaptic dysfunction in Alzheimer's disease: Mechanisms and therapeutic strategies. Pharmacol. Ther. doi:10.1016/j.pharmthera.2018.11.006.

  8. Chen Y, Zhang W, Zhao Z, Cai Y, Gong J, Kwok RTK, Lam JWY, Sung HHY, Williams ID and Tang BZ (2018). An Easily Accessible Ionic Aggregation-Induced Emission Luminogen with Hydrogen-Bonding-Switchable Emission and Wash-Free Imaging Ability. Angew. Chem. Int. Ed. Engl. 57(18):5011-5015.

  9. Cheng A, Zhao T, Tse KH, Chow HM, Cui Y, Jiang L, Du S, Loy MMT and Herrup K (2018). ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations. Proc. Natl. Acad. Sci. U S A. 115(2):E292-E301.

  10. Chu B, He A, Tian Y, He W, Chen P, Hu J, Xu R, Zhou W, Zhang M, Yang P, Li SSC, Sun Y, Li P, Hunter T and Tian R (2018). Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proc. Natl. Acad. Sci. U S A. 115(38):E8863-E8872.

  11. Dedic C, Hung TS, Shipley AM, Maeda A, Gardella T, Miller AL, Divieti Pajevic P, Kunkel JG and Rubinacci A(2018). Calcium fluxes at the bone/plasma interface: Acute effects of parathyroid hormone (PTH) and targeted deletion of PTH/PTH-related peptide (PTHrP) receptor in the osteocytes. Bone. 116:135-143.

  12. Egbenya DL, Hussain S, Lai YC, Xia J, Anderson AE and Davanger S (2018). Changes in synaptic AMPA receptor concentration and composition in chronic temporal lobe epilepsy. Mol. Cell. Neurosci. 92:93-103.

  13. Feng Z, Chen X, Zeng M and Zhang M (2018). Phase separation as a mechanism for assembling dynamic postsynaptic density signalling complexes. Curr. Opin. Neurobiol. 57:1-8.

  14. Feng Z, Zeng M, Chen X and Zhang M (2018). Neuronal Synapses: Microscale Signal Processing Machineries Formed by Phase Separation? Biochemistry. 57(17):2530-2539.

  15. Goto S, Shen X, Sun M, Hamano Y and Herrup K (2018). The Positive Effects of Viewing Gardens for Persons with Dementia. J Alzheimers Dis. 66(4):1705-1720.

  16. Gu S, Fu WY, Fu AKY, Tong EPS, Ip FCF, Huang X and Ip NY (2018). Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs. Sci. Rep. 8(1):7377 (1-7).

  17. Gu X, Zhang X, Ma H, Jia S, Zhang P, Zhao Y, Liu Q, Wang J, Zheng X, Lam JWY, Ding D and Tang BZ (2018). Corannulene-Incorporated AIE Nanodots with Highly Suppressed Nonradiative Decay for Boosted Cancer Phototheranostics In Vivo. Adv. Mater. 30(26):e1801065 (1-9).

  18. Gu Y, Zhao Z, Su H, Zhang P, Liu J, Niu G, Li S, Wang Z, Kwok RTK, Ni XL, Sun J, Qin A, Lam JWY and Tang BZ (2018). Exploration of biocompatible AIEgens from natural resources. Chem. Sci. 9(31):6497-6502.

  19. Hao HB, Webb SE, Yue J, Moreau M, Leclerc C and Miller AL (2018). TRPC3 is required for the survival, pluripotency and neural differentiation of mouse embryonic stem cells (mESCs). Sci. China Life Sci. 61(3):253-265.

  20. Hao HB, Webb SE, Yue J, Moreau M, Leclerc C and Miller AL (2018). The effect of pyrazole 3 treatment on the generation of intracellular Ca2+ transients and mitochondrial membrane potential, as well as the survival and neural differentiation of mouse embryonic stem cells. J Stem Cell. 13(1):1-21.

  21. He J, Xia M, Yeung PKK, Li J, Li Z, Chung KK, Chung SK and Xia J (2018). PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effect. Proc. Natl. Acad. Sci. U S A. 115(30):E7193-E7201.

  22. He S, An Y, Li X, Wei X, Sun Q, Wu Z and Qu JY (2018). In vivo metabolic imaging and monitoring of brown and beige fat. J Biophotonics. 11(8):e201800019.

  23. He S, Chen J, Jiang Y, Wu Y, Zhu L, Jin W, Zhao C, Yu T, Wang T, Wu S, Lin X, Qu JY, Wen Z, Zhang W and Xu J (2018). Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells. elife. 7:e36131 (1 of 18).

  24. Hu WH, Chan GK, Lou JS, Wu QY, Wang HY, Duan R, Cheng MY, Dong TT and Tsim KW (2018). The extract of Polygoni Cuspidati Rhizoma et Radix suppresses the vascular endothelial growth factor-induced angiogenesis. Phytomedicine. 42:135-143.

  25. Hu WH, Wang HY, Kong XP, Xiong QP, Poon KK, Xu L, Duan R, Chan GK, Dong TT and Tsim KW (2018). Polydatin suppresses VEGF-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling. FASEB J. 33(1):532-544.

  26. Hui CW, Song X, Ma F, Shen X and Herrup K (2018). Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice. J Neuroinflamm. 15(1):308.

  27. Ip NY (2018). Finding success by following your heart. Nat. Cell. Biol. 20(9):1003.

  28. Jiang M, Gu X, Kwok RTK, Li Y, Sung HHY, Zheng X, Zhang Y, Lam JWY, Williams ID, Huang X, Wong KS and Tang BZ (2018). Multifunctional AIEgens: Ready Synthesis, Tunable Emission, Mechanochromism, Mitochondrial, and Bacterial Imaging. Adv. Funct. Mater. 28(1):1704589 (1-11).

  29. Kelu JJ, Webb SE, Galione A and Miller AL (2018). TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons. Dev. Biol. 438(1):57-68.

  30. Kelu JJ, Webb SE, Galione A and Miller AL (2018). Characterization of ADP-ribosyl cyclase 1-like (ARC1-like) activity and NAADP signaling during slow muscle cell development in zebrafish embryos. Dev. Biol. 445(2):211-225.

  31. Lai KO and Ip NY (2018). Methods to Study the Signal Transduction of the Surface Receptor Tyrosine Kinase TrkB in Neurons. Methods Mol. Biol. 1722:211-222.

  32. Lee WWH, Zhao Z, Cai Y, Xu Z, Yu Y, Xiong Y, Kwok RTK, Chen Y, Leung NLC, Ma D, Lam JWY, Qin A and Tang BZ (2018). Facile access to deep red/near-infrared emissive AIEgens for efficient non-doped OLEDs. Chem. Sci. 9(28):6118-6125.

  33. Lei J, Sheng G, Cheung PP, Wang S, Li Y, Gao X, Zhang Y, Wang Y and Huang X (2018). Two symmetric arginine residues play distinct roles in Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc. Natl. Acad. Sci. U S A. 116(3):845-853.

  34. Li J, Zhu R, Chen K, Zheng H, Zhao H, Yuan C, Zhang H, Wang C and Zhang M (2018). Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol. 14(8):778-787.

  35. Li J, Mao Z, Huang J and Xia J (2018). PICK1 is essential for insulin production and the maintenance of glucose homeostasis. Mol. Biol. Cell. 29(5):587-596.

  36. Li Z, Liu H, Li J, Yang Q, Feng Z, Li Y, Yang H, Yu C, Wan J, Liu W and Zhang M (2018). Homer Tetramer Promotes Actin Bundling Activity of Drebrin. Structure. 27(1):27-38 e4 (1-17).

  37. Liu C, Zhou B, Geng Y, Tam DK, Rui F, Miao H, Xu N, Shi X, You Y, Hong Y, Tang BZ, Lo PK, Kuryavyi V and Zhu G (2018). A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K+ solution. Chem. Sci. 10(1):218-226.

  38. Lou WP, Mateos A, Koch M, Klussman S, Yang C, Lu N, Kumar S, Limpert S, Göpferich M, Zschaetzsch M, Sliwinski C, Kenzelmann M, Seedorf M, Maillo C, Senis E, Grimm D, Puttagunta R, Mendez R, Liu K, Hassan BA and Martin-Villalba A (2018). Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1. Front. Mol. Neurosci. 10:445 (1-15).

  39. Ma HT and Poon RYC (2018). TRIP13 Functions in the Establishment of the Spindle Assembly Checkpoint by Replenishing O-MAD2. Cell. Rep. 22(6):1439-1450.

  40. Nelson AD, Caballero-Florán RN, Rodríguez Díaz JC, Hull JM, Yuan Y, Li J, Chen K, Walder KK, Lopez-Santiago LF, Bennett V, McInnis MG, Isom LL, Wang C, Zhang M, Jones KS and Jenkins PM (2018). Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP. Mol. Psychiatry. doi:10.1038/s41380-018-0308-x.

  41. Ng LY, Ma HT, Liu JCY, Huang X, Lee N and Poon RYC (2018). Conditional gene inactivation by combining tetracycline-mediated transcriptional repression and auxin-inducible degron-mediated degradation. Cell Cycle. 18(2):238-248.

  42. Niu G, Zhang R, Kwong JPC, Lam JWY, Chen C, Wang J, Chen Y, Feng X, Kwok RTK, Sung HHY, Williams ID, Elsegood MRJ, Qu J, Ma C, Wong KS, Yu X and Tang BZ (2018). Specific Two-Photon Imaging of Live Cellular and Deep-Tissue Lipid Droplets by Lipophilic AIEgens at Ultralow Concentration. Chem. Mater. 30(14):4778-4787.

  43. Peng J, Wang W, Yu Y, Gu H and Huang X (2018). Clustering algorithms to Analyze Molecular Dynamics Simulation Trajectories for Complex Chemical and Biological Systems. Chin. J Chem. Phys. 31(4):404-420.

  44. Poon EN, Hao B, Guan D, Jun Li M, Lu J, Yang Y, Wu B, Wu SC, Webb SE, Liang Y, Miller AL, Yao X, Wang J, Yan B and Boheler KR (2018). Integrated transcriptomic and regulatory network analyses identify microRNA-200c as a novel repressor of human pluripotent stem cell-derived cardiomyocyte differentiation and maturation. Cardiovasc. Res. 114(6):894-906.

  45. Poon RYC (2018). Cyclin A. Encyclopedia of Signalling Molecules (Ed. Sangdun Choi). 2nd edition, pp1254-9.

  46. Qi J, Chen C, Zhang X, Hu X, Ji S, Kwok RTK, Lam JWY, Ding D and Tang BZ (2018). Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes. Nat. Commun. 9(1):1848.

  47. Qi J, Sun C, Li D, Zhang H, Yu W, Zebibula A, Lam JWY, Xi W, Zhu L, Cai F, Wei P, Zhu C, Kwok RTK, Streich LL, Prevedel R, Qian J and Tang BZ (2018). Aggregation-Induced Emission Luminogen with Near-Infrared-II Excitation and Near-Infrared-I Emission for Ultradeep Intravital Two-Photon Microscopy. ACS Nano. 12(8):7936-7945.

  48. Qi J, Sun C, Zebibula A, Zhang H, Kwok RTK, Zhao X, Xi W, Lam JWY, Qian J and Tang BZ (2018). Real-Time and High-Resolution Bioimaging with Bright Aggregation-Induced Emission Dots in Short-Wave Infrared Region. Adv. Mater. 30(12):e1706856 (1-9).

  49. Qi J, Chen C, Ding D and Tang BZ (2018). Aggregation-Induced Emission Luminogens: Union Is Strength, Gathering Illuminates Healthcare. Adv. Healthc. Mater. 7(20):e1800477.

  50. Qin W, Zhang P, Li H, Lam JWY, Cai Y, Kwok RTK, Qian J, Zheng W and Tang BZ (2018). Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration. Chem. Sci. 9(10):2705-2710.

  51. Shan Z, Tu Y, Yang Y, Liu Z, Zeng M, Xu H, Long J, Zhang M, Cai Y and Wen W (2018). Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nat. Commun. 9(1):737.

  52. So WK and Cheung TH (2018). Molecular Regulation of Cellular Quiescence: A Perspective from Adult Stem Cells and Its Niches. Methods Mol. Biol. 1686:1-25.

  53. Tse KH, Cheng A, Ma F and Herrup K (2018). DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia. Alzheimers Dement. 14(5):664-679.

  54. Tse MK, Hung TS, Chan CM, Wong T, Dorothea M, Leclerc C, Moreau M, Miller AL and Webb SE (2018). Identification of Ca2+ signaling components in neural stem/progenitor cells during differentiation into neurons and glia in intact and dissociated zebrafish neurospheres. Sci. China Life Sci. 61(11):1352-1368.

  55. Unarta IC, Zhu L, Tse CKM, Cheung PP, Yu J and Huang X (2018). Molecular mechanisms of RNA polymerase II transcription elongation elucidated by kinetic network models. Curr. Opin. Struct. Biol. 49:54-62.

  56. van der Wal E, Herrero-Hernandez P, Wan R, Broeders M, In 't Groen SLM, van Gestel TJM, van IJcken WFJ, Cheung TH, van der Ploeg AT, Schaaf GJ and Pijnappel WWMP (2018). Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies. Stem Cell Reports. 10(6):1975-1990.

  57. Wang G, Zhu H, Situ C, Han L, Yu Y, Cheung TH, Liu K and Wu Z (2018). p110α of PI3K is necessary and sufficient for quiescence exit in adult muscle satellite cells. EMBO J. 37(8). pii: e98239.

  58. Wang W, Liang T, Sheong FK, Fan X and Huang X (2018). An efficient Bayesian kinetic lumping algorithm to identify metastable conformational states via Gibbs sampling. J Chem. Phys. 149(7):072337.

  59. Wang Y, Shang Y, Li J, Chen W, Li G, Wan J, Liu W and Zhang M (2018). Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. elife. 7:e35677 (1 of 21).

  60. Wang Z, Cheng X, Qin A, Zhang H, Sun JZ and Tang BZ (2018). Multiple Stimuli Responses of Stereo-Isomers of AIE-Active Ethynylene-Bridged and Pyridyl-Modified Tetraphenylethene. J Phys. Chem. B. 122(7):2165-2176.

  61. Wen W and Zhang M (2018). Protein Complex Assemblies in Epithelial Cell Polarity and Asymmetric Cell Division. J Mol. Biol. 430(19):3504-3520.

  62. Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, Dore LC, Dong Q, Zheng W, Jin P, Wu H, Shen B, Zhuang X, He C, Liu K, Song H and Ming GL (2018). Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System. Neuron. 97(2):313-325.e6.

  63. Wong KM, Song J, Saini V and Wong YH (2018). Small molecules as drugs to upregulate metastasis suppressors in cancer cells. Curr. Med. Chem. 2018, 25, 1-22.

  64. Wu M, Tian HL, Liu X, Lai JHC, Du S and Xia J (2018). Impairment of Inhibitory Synapse Formation and Motor Behavior in Mice Lacking the NL2 Binding Partner LHFPL4/GARLH4. Cell. Rep. 23(6):1691-1705.

  65. Wu S, Xue R, Hassan S, Nguyen TML, Wang T, Pan H, Xu J, Liu Q, Zhang W and Wen Z (2018). Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors. Dev. Cell. 46(5):552-563.e4.

  66. Xie HQ, Xia Y, Xu T, Chen Y, Fu H, Li Y, Luo Y, Xu L, Tsim KWK and Zhao B (2018). 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces alterations in myogenic differentiation of C2C12 cells. Environ. Pollut. 235:965-973.

  67. Xu Z, Lo WS, Beck DB, Schuch LA, Oláhová M, Kopajtich R, Chong YE, Alston CL, Seidl E, Zhai L, Lau CF, Timchak D, LeDuc CA, Borczuk AC, Teich AF, Juusola J, Sofeso C, Müller C, Pierre G, Hilliard T, Turnpenny PD, Wagner M, Kappler M, Brasch F, Bouffard JP, Nangle LA, Yang XL, Zhang M, Taylor RW, Prokisch H, Griese M, Chung WK and Schimmel P (2018). Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function. Am. J Hum. Genet. 103(1):100-114.

  68. Yang X, Zhou S, Wu J, Liao Q, Wang C, Liu M, Qu L, Zhang Y, Cheng C, Chai R, Zhang K, Yu X, Huang P, Liu L, Xiong W, Chen S and Chen F (2018). Surgery-free video-oculography in mouse models: enabling quantitative and short-interval longitudinal assessment of vestibular function. Neurosci. Lett. 696:212-218.

  69. Ye F, Huang Y, Li J, Ma Y, Xie C, Liu Z, Deng X, Wan J, Xue T, Liu W and Zhang M (2018). An unexpected INAD PDZ tandem-mediated plcβ binding in Drosophila photo receptors. elife. 7:e41848 (1 of 23).

  70. Ye F, Zeng M and Zhang M (2018). Mechanisms of MAGUK-mediated cellular junctional complex organization. Curr. Opin. Struct. Biol. 48:6-15.

  71. Yeung RK, Xiang ZH, Tsang SY, Li R, Ho TYC, Li Q, Hui CK, Sham PC, Qiao MQ and Xue H (2018). Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation. Transl. Psychiatry. 8(1):128 (1-14).

  72. Yu C, Li CH, Chen S, Yoo H, Qin X and Park H (2018). Decreased BDNF Release in Cortical Neurons of a Knock-in Mouse Model of Huntington's Disease. Sci. Rep. 8(1):16976 (1-11).

  73. Zeng M, Chen X, Guan D, Xu J, Wu H, Tong P and Zhang M (2018). Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity. Cell. 174(5):1172-1187.e16.

  74. Zeng M, Ye F, Xu J and Zhang M (2018). PDZ Ligand Binding-Induced Conformational Coupling of the PDZ-SH3-GK Tandems in PSD-95 Family MAGUKs. J Mol. Biol. 430(1):69-86.

  75. Zeng X, Zhu L, Zheng X, Cecchini M and Huang X (2018). Harnessing complexity in molecular self-assembly using computer simulations. Phys. Chem. Chem. Phys. 20(10):6767-6776.

  76. Zhang P, Jiang T, Li Y, Zhao Z, Gong P, Cai L, Kwok RTK, Lam JWY, Gu X and Tang BZ (2018). Bio-orthogonal AIE Dots Based on Polyyne-Bridged Red-emissive AIEgen for Tumor Metabolic Labeling and Targeted Imaging. Chem Asian J. doi:10.1002/asia.201801609. [Epub ahead of print]

  77. Zhang P, Zhao Z, Li C, Su H, Wu Y, Kwok RTK, Lam JWY, Gong P, Cai L and Tang BZ (2018). Aptamer-Decorated Self-Assembled Aggregation-Induced Emission Organic Dots for Cancer Cell Targeting and Imaging. Anal. Chem. 90(2):1063-1067.

  78. Zhang R, Sung SHP, Feng G, Zhang CJ, Kenry, Tang BZ and Liu B (2018). Aggregation-Induced Emission Probe for Specific Turn-On Quantification of Soluble Transferrin Receptor: An Important Disease Marker for Iron Deficiency Anemia and Kidney Diseases. Anal. Chem. 90(2):1154-1160.

  79. Zhang Y, Jiang M, Han T, Xiao X, Chen W, Wang L, Wong KS, Wang R, Wang K, Tang BZ and Wu K (2018). Aggregation-Induced Emission Luminogens as Color Converters for Visible-Light Communication. ACS Appl. Mater. Interfaces. 10(40):34418-34426.

  80. Zhao Z, Gao S, Zheng X, Zhang P, Wu W, Kwok RTK, Xiong Y, Leung NLC, Chen Y, Gao X, Lam JWY and Tang BZ (2018). Rational Design of Perylenediimide-Substituted Triphenylethylene to Electron Transporting Aggregation-Induced Emission Luminogens (AIEgens) with High Mobility and Near-Infrared Emission. Adv. Funct. Mater. 28(11):1705609 (1-9).

  81. Zhou X, Chen Y, Mok KY, Zhao Q, Chen K, Chen Y, Hardy J, Li Y, Fu AKY, Guo Q, Ip NY and Alzheimer’s Disease Neuroimaging Initiative (2018). Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis. Proc. Natl. Acad. Sci. USA. 115(8):1697-1706.

  The State Key Laboratory of Neuroscience aims to become one of the world’s leading research hub in neuroscience research. From Bench to Bedside - Towards The Treatment of Debilitating Neurological Disorders Through The Discovery of Novel Neuro-Drugs.  
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