spacer   spacer
 
topbar Home Contact Us Sitemap HKUST
 
 
spacer English l 繁體 l 简体  
 
  State Key Labratory of Molecular Neuroscience  
 
About SKL
People
Research
Publications
List of Seminars
Honors and Awards
News & Events
Links & Resources
line
Research Publications in 2013   spacer
   
  1. Cao M, Mao Z, Kam C, Xiao N, Cao X, Shen C, Cheng KK, Xu A, Lee KM, Jiang L and Xia J (2013). PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance. PLoS Biol. 11(4):e1001541.

  2. Chan CM, Miller AL and Webb SE (2013). Reconstitution of holo-aequorin with apoaequorin mRNA and coelenterazine in zebrafish embryos. Cold Spring Harb. Protoc. 2013(5):456-60.

  3. Chan KH and Wong YH (2013). A molecular and chemical perspective in defining melatonin receptor subtype selectivity. Int. J. Mol. Sci. 14(9):18385-18406.

  4. Chan KH, Chen YH, Zhang Y, Wong YH and Dun NJ (2013). Angiotensin-[1-12] interacts with angiotensin type I receptors. Neuropharmacol. 81C:267-273.

  5. Chan KH, Cheung AST, Ho MKC and Wong YH (2013). Development of novel melatoninergics as circadian rhythm sleep disorder therapeutics. In: New Developments in Melatonin Research (Acuna-Castroviejo D, Rusanova I, and Escames G eds.), pp53-76, Nova Science Publishers, Inc.

  6. Chan KH, Hu Y, Ho MKC and Wong YH (2013). Characterization of substituted phenylpropylamides as highly selective agonists at the melatonin MT2 receptor. Curr. Med. Chem. 20:289-300.

  7. Chen J and Zhang M (2013). The Par3/Par6/aPKC complex and epithelial cell polarity. Exp. Cell Res. 319(10):1357-1364.

  8. Chen M, Ma X, Chen X, Jiang M, Song H and Guo Z (2013). Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli. J Bacteriol. 195(12):2768-75.

  9. Chen S, Chen J, Shi H, Wei M, Castaneda-Castellanos DR, Bultje RS, Pei X, Kriegstein AR, Zhang M and Shi SH (2013). Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity. Dev. Cell. 24(1):26-40.

  10. Chen X, Shen XY, Guan E, Liu Y, Qin A, Sun JZ and Tang BZ (2013). A pyridinyl-functionalized tetraphenylethylene fluorogen for specific sensing of trivalent cations. Chem. Commun. 49:1503-1505.

  11. Chen Y, Fu AK and Ip NY (2013). Axin: An emerging key scaffold at the synapse. IUBMB Life. 65(8):685-91.

  12. Choi RC, Chen VP, Luk WK, Yung AW, Ng AH, Dong TT and Tsim KW (2013). Expression of cAMP-responsive element binding proteins (CREBs) in fast- and slow-twitch muscles: a signaling pathway to account for the synaptic expression of collagen-tailed subunit (ColQ) of acetylcholinesterase at the rat neuromuscular junction. Chem. Biol. Interact. 203(1):282-286.

  13. Choi RC, Chu GK, Siow NL, Yung AW, Yung LY, Lee PS, Lo CC, Simon J, Dong TT, Barnard EA and Tsim KW (2013). Activation of UTP-sensitive P2Y2 receptor induces the expression of cholinergic genes in cultured cortical neurons: a signaling cascade triggered by Ca2+ mobilization and extracellular regulated kinase phosphorylation. Mol. Pharmacol. 84(1):50-61.

  14. Choi RC, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TT and Tsim KW (2013). Synergistic action of flavonoids, baicalein, and daidzein in estrogenic and neuroprotective effects: A development of potential health products and therapeutic drugs against Alzheimer's disease. Evid. Based Complement. Alternat. Med. 2013:635694.

  15. Chow JPH, Man WY, Mao M, Chen H, Cheung F, Nicholls J, Tsao SW, Lung ML and Poon RYC (2013). PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy. Mol. Cancer Ther. 12(11):2517-2528.

  16. Ding D, Li K, Liu B and Tang BZ (2013). Bioprobes based on AIE fluorogens. Acc. Chem. Res. 46(11): 2441-2453.

  17. Fang WQ, Chen WW, Fu AKY and Ip NY (2013). Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex. Neuron. 79:665-679. [Highlighted in F1000Prime http://f1000.com/prime/718084606#recommendations; and selected by Neuron to be accompanied with a video abstract. The video is featured on the Neuron website (http:www.cell.com/neuro/abstract/S0896-6273(13)00533-3); and is accessible in YouTube channel (http://www.youtube.com/watch?v-xBKhD9P_FUc)].

  18. Fu AKY, Hung KW, Wong HHW, Fu WY and Ip NY (2013). Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death. NeuroSignals. 21(1-2):55-60.

  19. Gao M, Lam JWY, Li J, Chan CYK, Chen YL, Zhao N, Han TY and Tang BZ (2013). Stoichiometric imbalance-promoted synthesis of polymers containing highly substituted naphthalenes: rhodium-catalyzed oxidative polycoupling of arylboronic acids and internal diynes. Polym. Chem. 4:1372-1380.

  20. Han T, Hong Y, Xie N, Chen S, Zhao N, Zhao E, Lam JWY, Sung HHY, Dong Y, Tong B and Tang BZ (2013). Defect-sensitive crystals based on diaminomaleonitrile-functionalized Schiff base with aggregation-enhanced emission. J. Mater. Chem. C. 1:7314-7320.

  21. Han T, Lam JWY, Zhao N, Gao M, Yang Z, Zhao E, Dong Y and Tang BZ (2013). A fluorescence-switchable luminogen in the solid state: a sensitive and selective sensor for the fast “turn-on” detection of primary amine gas. Chem. Commun. 49:4848-4850.

  22. Han X and Poon RYC (2013). Critical differences between isoforms of securin reveal mechanisms of separase regulation. Mol. Cell. Biol. 33(17):3400-3415.

  23. Heng LP, Hu RR, Chen SJ, Li MC, Jiang L and Tang BZ (2013). Ordered honeycomb structural interfaces for anticancer cells growth. Langmuir. 29:14947-14953.

  24. Hu RR, Lam JWY, Liu Y, Zhang X and Tang BZ (2013). Aggregation-induced emission of tetraphenylethene–hexaphenylbenzene adducts: Effects of twisting amplitude and steric hindrance on light emission of nonplanar fluorogens. Chemistry. 19(18):5617-5624.

  25. Hu RR, Lam JWY and Tang BZ (2013). Recent progress in the development of new acetylenic polymers. Macromol. Chem. Phys. 214(2):175-187.

  26. Hu RR, Lam JWY, Yu Y, Sung HHY, Williams ID, Yuen MMF and Tang BZ (2013). Facile synthesis of soluble nonlinear polymers with glycogen-like structures and functional properties from “simple” acrylic monomers. Polym. Chem. 4:95-105.

  27. Hu Y, Zhang J, Chandrashankra O, Ip FCF and Ip NY (2013). Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors. Bioorg. Med. Chem. 21(3):676-683.

  28. Hu Y, Zhu J, Chan KH and Wong YH (2013). Development of substituted N-[3-(3-Methoxylphenyl)propyl] amides as MT2-selective melatonin agonists: improving metabolic stability. Bioorg. Med. Chem. 21:547-552.

  29. Jia Y, Fong KW, Choi YK, See SS and Qi RZ (2013). Dynamic recruitment of CDK5RAP2 to centrosomes requires its association with dynein. PLoS One. 8(7):e68523.

  30. Jim CKW, Lam JWY, Qin AJ, Leung CWT, Liu JZ, Sung HHY, Williams ID and Tang BZ (2013). Ferrocene-decorated hyperbranched poly(aroxycarbonylphenylene)s: synthesis, light refraction, photopatterning and precursor to magnetic ceramics. J. Inorg. Organomet. Polym. 23:147-157.

  31. Lai KO and Ip NY (2013). Structural plasticity of dendritic spines: the underlying mechanisms and its dysregulation in brain disorders. Biochim. Biophys. Acta. 1832(12):2257-2263.

  32. Lau WWI, Chan ASL, Poon LSW, Zhu J and Wong YH (2013). Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms. Cell Commun. Signal. 11:22.

  33. Li J, Liu JZ, Lam JWY and Tang BZ (2013). Poly(arylene ynonylene) with an aggregation-enhanced emission characteristic: a fluorescent sensor for both hydrazine and explosive detection. RSC Adv. 3(22):8193-8196.

  34. Li K, Qin W, Ding D, Tomczak N, Geng JL, Liu RR, Liu JZ, Zhang XH, Liu HW, Liu B and Tang BZ (2013). Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing. Sci. Rep. 3:1150.

  35. Li M, Hong Y, Wang Z, Chen S, Gao M, Kwok RTK, Qin W, Lam JWY, Zheng Q and Tang BZ (2013). Fabrication of chitosan nanoparticles with aggregation-induced emission characteristics and their applications in long-term live cell imaging. Macromol. Rapid Comm. 34(9):767-771.

  36. Li M, Lam JWY, Mahtab F, Chen S, Zhang W, Hong Y, Xiong J, Zheng Q and Tang BZ (2013). Biotin-decorated fluorescent silica nanoparticles with aggregation-induced emission characteristics: fabrication, cytotoxicity and biological applications. J. Mater. Chem. B. 1:676-684.

  37. Li X, Mao Z, Wu M and Xia J (2013). Rescuing infertility of Pick1 knockout mice by generating testis-specific transgenic mice via testicular infection. Sci. Rep. 3:2842.

  38. Liu Y, Lv Y, Xi H, Zhang X, Chen S, Lam JWY, Kwok RTK, Mahtab F, Kwok HS, Tao X and Tang BZ (2013). Enlarged tetrasubstituted alkenes with enhanced thermal and optoelectronic properties. Chem. Commun. 49:7216-7218.

  39. Mei J, Wang Y, Tong J, Wang J, Qin A, Sun JZ and Tang BZ (2013). Discriminatory detection of cysteine and homocysteine based on dialdehyde-functionalized aggregation-induced emission fluorophores. Chem. Eur. J. 19(2):613-620.

  40. Ng YP, Chen YW, Hu YQ, Ip FCF and Ip NY (2013). Olean-12-eno[2,3-c][1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines. PLOS One. 8(5):e63580.

  41. Pan Z, Shang Y, Jia M, Zhang L, Xia C, Zhang M, Wang W and Wen W (2013). Structural and biochemical characterization of the interaction between LGN and Frmpd1. J. Mol. Biol. 425:1039-1049.

  42. Pan Z, Zhu J, Shang Y, Wei Z, Jia M, Xia C, Wen W, Wang W and Zhang M (2013). An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs. Structure. 21(6):1007-1017.

  43. Poon RYC (2013). Aurora B: hooking up with cyclin-dependent kinases. Cell Cycle. 12(7):1019-20.

  44. Shen Y, Fu WY, Cheng EY, Fu AKY and Ip NY (2013). Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a PKA-dependent mechanism. J. Neurosci. 33(2):464-472.

  45. Sun JP, Liu W, Li L, Chen JH, Wu M, Zhang YY, Leung AYH, Zhang WQ, Wen ZL and Laio WJ (2013). Suppression of Pu.1 function results in expanded myelopoiesis in zebrafish. Leukemia. 27:1913-1917. (Co-correspondent author).

  46. Sun JZ, Qin AJ and Tang BZ (2013). Functional polyacetylenes: hybrids with carbon nanotubes. Polym. Chem. 4:211-223.

  47. Sun Y, Song H, Li J, Li Y, Jiang M, Zhou J and Guo Z (2013). Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily. PLoS One. 8(4):e63095.

  48. Tsang SY, Zhong S, Mei L, Chen J, Ng SK, Pun FW, Zhao C, Jing B, Chark R, Guo J, Tan Y, Li L, Wang C, Chew SH and Xue H (2013). Social cognitive role of schizophrenia candidate gene GABRB2. PLoS One. 8(4):e62322.

  49. Tse MK and Wong YH (2013). The neuronal functions of activators of G protein signaling. Neurosignals. 21:259-271.

  50. Tso PH, Wang Y, Yung LY, Tong Y, Lee MMK and Wong YH (2013). RGS19 inhibits Ras signaling through Nm23H1-mediated phosphorylation of the kinase suppressor of Ras. Cell. Signal. 25:1064-1074.

  51. Wang Q, Chen M, Yao B, Wang J, Mei J, Sun JZ, Qin AJ and Tang BZ (2013). A polytriazole synthesized by 1,3-Dipolar polycycloaddition showing aggregation-enhanced emission and utility in explosive detection.Macromol. Rapid Comm. 34(9):796-802.

  52. Wang Q, Li HK, Wei Q, Sun JZ, Wang J, Zhang XA, Qin AJ and Tang BZ (2013). Metal-free click polymerizations of activated azide and alkynes. Polym. Chem. 4:1396-1401.

  53. Wang Y, Tong Y, Tso PH and Wong YH (2013). Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis. Cancer Lett. 339:33-41.

  54. Webb SE and Miller AL (2013). Ca2+ signaling during activation and fertilization in the eggs of teleost fish. Cell Calcium. 53(1):24-31.

  55. Webb SE and Miller AL (2013). Calcium signaling in extraembryonic domains during early teleost development. Int. Rev. Cel. Mol. Bio. 304:369-418.

  56. Webb SE and Miller AL (2013). Microinjecting holo-aequorin into dechorionated and intact zebrafish embryos. Cold Spring Harb. Protoc. 2013(5):447-455.

  57. Webb SE, Chan CM and Miller AL (2013). Introduction of aequorin into zebrafish embryos for recording Ca2+ signaling events during the first 48 hours of development. Cold Spring Harb. Protoc. 2013(5):383-386.

  58. Webb SE, Goulet C, Chan CM, Yuen YF and Miller AL (2013). Biphasic assembly of the contractile apparatus during the first two cell division cycles in zebrafish embryos. Zygote. 27:1-11.

  59. Webb SE, Karplus E and Miller AL (2013). Retrospective on the development of aequorin and aequorin-based imaging to visualize changes in intracellular free Ca2+. Mol Reprod Dev. doi: 10.1002/mrd.22298. [Epub ahead of print].

  60. Wei Z and Zhang M (2013). Decorating proteins with "sweets" is a flexible matter. Structure. 21(1):1-2.

  61. Wei Z, Liu X, Yu C and Zhang M (2013). Structural basis of cargo recognitions for class V Myosins. PNAS. 110:11314-11319.

  62. Wong CCK and Wong YH (2013). High-throughput screening in traditional Chinese medicine-based drug discovery. In: Antitumor Potential and Other Emerging Medicinal Properties of Natural Compounds, (Fang EF and Ng TB eds.), pp387-404, Springer Publisher.

  63. Ye F and Zhang M (2013). Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures. Biochem. J. 455(1):1-14.

  64. Yu Y, Li J, Chen S, Hong Y, Ng KM, Luo KQ and Tang BZ (2013). Thiol-reactive molecule with dual-emission-enhancement property for specific prestaining of cysteine containing proteins in SDS-PAGE. ACS Appl. Mater. Inter. 5(11):4613-4616.

  65. Yuan WZ, Tan Y, Gong Y, Lu P, Lam JWY, Shen XY, Feng C, Sung HHY, Lu Y, Williams ID, Sun JZ, Zhang YM and Tang BZ (2013). Synergy between twisted conformation and effective intermolecular interactions: strategy for efficient mechanochromic luminogens with high contrast. Adv. Mater. 25(20):2837-2843.

  66. Yuen MY, Webb SE, Chan CM, Thisse B, Thisse C and Miller AL (2013). Characterization of Ca2+ signaling in the external yolk syncytial layer during the late blastula and early gastrula periods of zebrafish development. Biochim. Biophys. Acta. 1833(7):1641-56.

  67. Zeng Y, Yan B, Sun QQ, Teh SK, Zhang W, Wen ZL and Qu JY (2013). Label-free in vivo imaging of human leukocytes using two-photon excited endogenous fluorescence. J Biomed. Opt. 18:040504.

  68. Zha G, Chen VP, Luk WK, Zou X, Choi RC and Tsim KW (2013). Characterization of acetylcholinesterase in Hong Kong oyster (Crassostrea hongkongensis) from South China Sea. Chem. Biol. Interact. 203:277-281.

  69. Zhang Y, Wang W, Chen J, Zhang K, Gao F, Gao B, Zhang S, Dong M, Besenbacher F, Gong W, Zhang M, Sun F and Feng W (2013). Structural insights into the intrinsic self-assembly of Par-3 N-Terminal domain. Structure. 21:997-1006.

  70. Zhao Z, Chang Z, He B, Chen B, Deng C, Lu P, Qiu H and Tang BZ (2013). Aggregation-induced emission and efficient solid-State fluorescence from tetraphenylethene-based N,C-Chelate four-coordinate organoborons. Chem. Eur. J. 19(35):11512-11517.

  71. Zhao ZJ, Chen B, Geng JL, Chang ZF, Aparicio-Ixta L, Nie H, Goh CC, Ng LG, Qin AJ, Ramos-Ortiz G, Liu B and Tang BZ (2013). Red emissive biocompatible nanoparticles from tetraphenylethene-decorated BODIPY luminogens for two-photon excited fluorescence cellular imaging and mouse brain blood vascular visualization. Part. Part. Syst. Charact. 31:481-491.

  72. Zhao ZJ, Lam JWY and Tang BZ (2013). Self-assembly of organic luminophores with gelation-enhanced emission characteristics. Soft Matter. 9:4564-4579.

  73. Zhen FH, Lan YH, Yan B, Zhang WQ and Wen ZL (2013). Hemogenic endothelium specification and hematopoietic stem cell maintenance employ distinct Scl isoforms. Development. 140:3977-3985.

  74. Zhu KY, Xu SL, Choi RC, Yan AL, Dong TT and Tsim KW (2013). Kai-xin-san, a chinese herbal decoction containing ginseng radix et rhizoma, polygalae radix, acori tatarinowii rhizoma, and poria, stimulates the expression and secretion of neurotrophic factors in cultured astrocytes. Evid. Based Complement. Alternat. Med. 2013:731385.

  75. Zuo H, Chan ASL, Ammer H and Wong YH (2013). Activation of Gαq subunits up-regulates the expression of the tumor suppressor Fhit. Cell. Signal. 25:2440-2452.

  76. Zuo H, Chan GPW, Zhu J, Yeung WWS, Chan ASL, Ammer H and Wong YH (2013). Activation state-dependent interaction between Gαq subunits and the Fhit tumor suppressor. Cell Commun. Signal. 11:59.

 
spacer
Back
   
 
  The State Key Laboratory of Neuroscience aims to become one of the world’s leading research hub in neuroscience research. From Bench to Bedside - Towards The Treatment of Debilitating Neurological Disorders Through The Discovery of Novel Neuro-Drugs.  
spacer
spacer
Copyright © State Key Laboratory of Molecular Neuroscience, HKUST