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  State Key Labratory of Molecular Neuroscience  
 
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Research Publications in 2011   spacer
   
  1. Cheung CY, Webb SE, Love DR and Miller AL (2011). Visualization, characterization and modulation of Ca2+ signaling during the development of slow muscle cells in intact zebrafish embryos. Int. J Dev. Biol. 55:153-174.

  2. Cheung ZH and Ip NY (2011). Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives. J Neurochem. 118:317-325. Invited.

  3. Cheung ZH and Ip NY (2011). From understanding synaptic plasticity to the development of cognitive enhancers.  Int. J Neuropsychoph. 6:1-10. Invited.

  4. Du LS, Xu J, Li XL, Ma N, Liu YM, Peng JR, Osato M, Zhang WQ and Wen Z (2011). Rumba and Haus3 are essential factors for maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis. Development. 138:619-629.

  5. Fang, WQ, Ip JP, Li R, Ng YP, Lin SC, Chen Y, Fu AK and Ip NY (2011). Cdk5-mediated phosphorylation of Axin directs axon formation during cerebral cortex development. J Neurosci. 31:13613-13624.

  6. Fu AK, Hung KW, Fu WY, Shen C, Chen Y, Xia J, Lai KO and Ip NY (2011). APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity. Nat Neurosci. 14(2):181-189.

  7. Fu GM, Shi SP, Ip FC, Pang HH and Ip NY (2011). A new carotenoid glycoside from Rehmannia glutinosa. Nat. Prod. Res. 25:1213-1218.

  8. Fu WY, Cheng K, Fu KY and Ip NY (2011). Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development. Neurosci. 180:353-359.

  9. He L, Zhang Z, Yu Y, Ahmed S, Cheung NS and Qi RZ (2011). The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein. Cell Mol. Life Sci.. 68(9):1633-1643.

  10. Huo L, Wen W, Wang R, Kam C, Xia J, Feng W and Zhang M (2011). Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration. EMBO J. 30(4):665-678.

  11. Li L, Jin H, Xu J, Shi Y and Wen Z (2011). Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis. Blood. 117(4):1359-1369.

  12. Li PP, Chen C, Lee CW, Madhavan R and Peng HB (2011). Axonal filopodial asymmetry induced by synaptic target. Mol. Biol. Cell. 22(14):2480-2490.

  13. Li Y, Wan OW, Xie W and Chung KKK (2011). P32 regulates mitochondrial morphology and dynamics through parkin. Neurosci. 199:346-358.

  14. Liu AMF, Lo RKH, Guo EX, Ho MKC, Ye RD and Wong YH (2011). Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling. BMC Structural Biology. 11:17.

  15. Liu W, Wen W, Wei Z, Yu J, Ye F, Liu CH, Hardie RC and Zhang M (2011). The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye. Cell. 145(7):1088-1101.

  16. Mei H, Ho MK, Yung LY, Wu Z, Ip NY and Wong YH (2011). Expression of Gα(z) in C2C12 cells restrains myogenic differentiation. Cell Signal. 23(2):389-97.

  17. Tso PH, Yung LY, Wang YC and Wong YH (2011). RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. Cancer Letters. 309:199-208.

  18. Webb SE, Fluck RA and Miller AL (2011). Calcium signaling during the early development of medaka and zebrafish. Biochimie. 93:2112-2125.

  19. Wei Z, Yan J, Lu Q, Pan L and Zhang M (2011). Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain. Proc. Natl. Acad. Sci. USA.. 108:3572-3577.

  20. Wei Z, Zheng S, Spangler SA, Yu C, Hoogenraad CC and Zhang M (2011). Liprin-mediated large signaling complex organization revealed by the Liprin-α/CASK and Liprin-α/Liprin-β complex structures. Mol. Cell. 43:586-598.

  21. Wong AS, Cheung ZH and Ip NY (2011). Molecular machinery of macroautophagy and its deregulation in diseases. Biochim. Biophys. Acta. 1812(11):1490-1497.

  22. Wong AS, Lee RH, Cheung AY, Yeung PK, Chung SK, Cheung ZH and Ip NY (2011). Cdk5-medicated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson’s disease.  Nat. Cell Biol. 13(5):568-579.

  23. Wu L, Pan L, Wei Z and Zhang M (2011). Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo. Science. 331(6018):757-760.

  24. Yu H, Hu Y, Ip FCF, Zuo Z, Han YF and Ip NY (2011). Intestinal transport of bis(12)-hupyridone in caco-2 cells and its improved permeability by the surfactant Brij-35. Biopharm. Drug Dispos. 32:140-150.

  25. Zhang HL and Peng HB (2011). Mechanism of acetylcholine receptor cluster formation induced by DC electric field. PLoS ONE. 6(10):e26805.

  26. Zhang J, Webb SE, Ma LH, Chan CM and Miller AL (2011). Necessary role for intracellular Ca2+ transients in initiating the apical-basolateral thinning of enveloping layer cells during the early blastula period of zebrafish development. Dev. Growth Diff. 53:679-696.

  27. Zhang YY, Jin H, Li L, Qin XF and Wen Z (2011). cMyb regulates hematopoietic stem/progenitor cell migration during zebrafish hematopoiesis. Blood. 118:4093-4101.

  28. Zhu J, Hu YQ, Ho MKC and Wong YH (2011). 3-Methoxylphenylpropyl amides as novel receptor subtype-selective melatoninergic ligands: characterization of physicochemical and pharmacokinetic properties. Xenobiotica. 41(1):35-45.

  29. Zhu J, Wen W, Zheng Z, Shang Y, Wei Z, Xiao Z, Pan Z, Du Q, Wang W and Zhang M (2011). LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways. Mol. Cell. 43:418-431.

 
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  The State Key Laboratory of Neuroscience aims to become one of the world’s leading research hub in neuroscience research. From Bench to Bedside - Towards The Treatment of Debilitating Neurological Disorders Through The Discovery of Novel Neuro-Drugs.  
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